Neuronal Synchronization

Activity in the brain is noisy but highly organized. Particularly notable are brain “rhythms,” generated by rhythmically modulated activity of neurons and readily detectable in the EEG. Using a combination of electrophysiology, computational modeling and theoretical frameworks, we study the mechanisms underlying theta and gamma oscillations.

Relevant Publications

Gamma Oscillations

Tikidji-Hamburyan RA*, Martinez JJ*, White JA†, and Canavier CC† (2015) Resonant interneurons can increase robustness of gamma oscillations. Journal of Neuroscience 35: 15682-95.

Economo MN and White JA (2012) Membrane properties and the balance between excitation and inhibition control gamma-frequency oscillations arising from feedback inhibition. PLoS Computational Biology 8: e1002354

Theta Oscillations

Fernandez FR, Malerba P, Bressloff PC, and White JA (2013) Entorhinal stellate cells show preferred spike phase-locking to theta inputs that is enhanced by correlations in synaptic activity. Journal of Neuroscience 33: 6027-6040.

Burton BG, Economo MN, Lee J, and White JA (2008) Development of theta rhythmicity in entorhinal stellate cells of the juvenile rat. Journal of Neurophysiology 100: 3144-3157.